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The side-chain hydroxyl group also participates in phase II conjugation reactions, facilitating the formation of sulfate and glucuronide metabolites after oral intake [29,30,31,32]

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Potential side effects Possible side effects of supplementary l-carnitine include, but are not limited to: Gut disturbance: l-carnitine does not have an established upper intake level, although doses above 3g per day may cause nausea, vomiting, abdominal cramps and diarrhoea Coronary artery disease: some research suggests l-carnitine may be linked to an increased risk of coronary artery disease and heart failure, especially in men and those who eat meat

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