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Stopping too quickly, or stopping altogether, can be intolerable and even life-threatening in rare cases

Besides the anti-inflammatory effects, omega-3 fatty acids are also involved in transcription factor activity, intracellular signaling pathways, and gene expression (127, 129)

Lifestyle factors and cardiovascular risk Life Sciences (2020)

In humans, direct ANP infusion at maximal dose increases lipolysis greater than 10-fold (114) and can decreases blood pressure, and increases post-prandial lipid oxidation and energy expenditure (111), suggesting therapeutic benefits of ANP treatment are possible in man

Munzel T, Daiber A, Ullrich V, Mulsch A