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Gastroenterology 115:357369 Garcia-Lafuente A, Antolin M, Guarner F, Crespo E, Salas A, Forcada P, Laguarda M, Gavalda J et al (1997) Incrimination of anaerobic bacteria in the induction of experimental colitis

His-UBE2m protein gel strip was digested in the gel using -lytic protease (MilliporeSigma, A6362) and then analyzed using LC-MS/MS in collaboration with SpecAlly (Wuhan, China)

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Binding the toxin to glutathione allows it to be easily moved out of the cell via several different transmembrane efflux pumps

Inhibition of GCH1 leads to a dysfunctional state of BH4 biosynthesis, resulting in ROS accumulation and ferroptosis (41)