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Mitochondrial iron and ROS accumulation mediates cardiomyocyte death induced by simulated ischemia/reperfusion or doxorubicin To further investigate the role of mitochondrial iron and ROS in pathological conditions associated with elevated oxidative stress 17, 19 , cardiomyocytes were subjected to simulated ischemia and reperfusion (sI/R) or the chemotherapeutic agent doxorubicin (DOX)

223 Platelets and endothelial cells Platelets and endothelial cells play pivotal roles in liver regeneration, interacting closely to coordinate vascular remodeling and tissue recovery

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