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Mentioned reactive aldehydes, as well as isoprostanes, particularly F2-isoprostanes, are bioactive compounds formed via nonenzymatic peroxidation of arachidonic acid (AA), serving as reliable biomarkers for assessing oxidative stress status in various clinical conditions 89

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GABA A receptors were blocked by 10 M SR95531 (Tocris)

59 Furthermore, chronic inflammasome activation has been linked to metabolic disorders such as obesity and type 2 diabetes, contributing to systemic inflammation and hepatic dysfunction