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As a consequence of this chemistry, O 2 - -dependent, SOD-sensitive chemiluminescence can be generated in cellular systems that do not generate ROS themselves but are simply capable of redox-cycling the probe (lucigenin) used to detect this activity

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Decreased hippocampal NMDA, but not kainate or AMPA receptors in bipolar disorder

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Copper has a complex role in oxidative biology participating in both prooxidant chemistry (where free or weakly bound copper can catalyze damaging reactive-oxygen-species generation) and antioxidant chemistry (as the cofactor of Cu/Zn superoxide dismutase)