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This can lead to a range of symptoms, including fatigue, weight gain, depression, and cognitive impairment

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Semaglutide Side Effects Semaglutides side effects are predominantly gastrointestinal: Nausea reported by 4044% of participants, most common during dose escalation Diarrhea reported by 2430% Vomiting reported by 1824% Constipation reported by 1024% Abdominal pain reported by 515% Headache reported by 1014% Fatigue reported by 511% Gastrointestinal side effects typically improve significantly after the first 48 weeks and during stable dosing periods