It's a developing area, and staying updated on clinical trials.gov will be key
Hydration is particularly important, as older adults already have a diminished thirst response and may be at increased risk of dehydration when appetite and fluid intake decrease
It's not in my handout for POTS patients that says you have to sleep with the head of the bed up

| State | Average Cost | | ---------- | ---------- | | Alabama | $2,000-$8,000 | | Alaska | $1,000-$20,000 | | Arizona | $2,000-$8,500 | | Arkansas | $1,600-$13,000 | | California | $1,000-$20,000 | | Colorado | $2,000-$8,500 | | Connecticut | $2,000-$16,000 | | Delaware | $2,000-$16,000 | | Florida | $2,000-$8,000 | | Georgia | $2,000-$8,000 | | Hawaii | $1,000-$20,000 | | Idaho | $2,000-$8,500 | | Illinois | $1,600-$13,000 | | Indiana | $2,000-$16,000 | | Iowa | $1,600-$13,000 | | Kansas | $1,000-$20,000 | | Kentucky | $2,000-$16,000 | | Louisiana | $1,600-$13,000 | | Maine | $2,000-$16,000 | | Maryland | $2,000-$16,000 | | Massachusetts | $2,000-$16,000 | | Michigan | $2,000-$16,000 | | Minnesota | $1,600-$13,000 | | Mississippi | $2,000-$8,000 | | Missouri | $1,600-$13,700 | | Montana | $1,000-$20,000 | | Nebraska | $1,600-$13,000 | | Nevada | $1,000-$20,000 | | New Hampshire | $2,000-$16,000 | | New Jersey | $2,000-$16,000 | | New Mexico | $2,000-$8,500 | | New York | $2,000-$16,000 | | North Carolina | $2,000-$8,000 | | North Dakota | $1,600-$13,000 | | Ohio | $2,000-$16,000 | | Oklahoma | $1,600-$13,000 | | Oregon | $1,000-$20,000 | | Pennsylvania | $2,000-$16,000 | | Rhode Island | $2,000-$16,000 | | South Carolina | $1,000-$20,000 | | South Dakota | $1,600-$13,000 | | Tennessee | $2,000-$8,000 | | Texas | $2,000-$8,500 | | Utah | $2,000-$8,500 | | Vermont | $1,200-$10,000 | | Virginia | $2,000-$16,000 | | Washington | $1,000-$20,000 | | Washington DC | $2,000-$16,000 | | West Virginia | $2,000-$16,000 | | Wisconsin | $1,600-$13,000 | | Wyoming | $2,000-$8,500 | these states are presented as national averages as specific information is not available | Country | Average Cost | | ---------- | ---------- | | Canada | $1,000 to $9,000 | | Mexico | $1,000 to $5,000 | | Colombia | $900 to $4,500 | | United Kingdom | $1,500 to $8,500 | | Australia | $1,000 to $9,000 | | Japan | $1,000 to $8,000 | | United Arab Emirates | $1,000 to $9,000 | The difference in the definitions is the key takeaway

As shown in Figure 7 , in mock- and GSTP1 -transfected HepG2 cells dose- and time- dependent up-regulations of CHOP-GFP signal were detected following treatment with AQ-QI or DEAQ-QI