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Astragaloside IV alleviates tacrolimus-induced chronic nephrotoxicity via p62-keap1-nrf2 pathway

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In the last decade, however, technologic advancements in chromatographic and analytic techniques have allowed for a tremendous growth in the field of metabolomics, making it possible to identify hundreds, and sometimes thousands, of unique human analytes, leading to unprecedented insight into countless biochemical pathways ( Figure 2 )

The Role of Glutathione Metabolism in Chronic Illness Development and Its Potential Use as a Novel Therapeutic Target", Cureus , 14 (9), e29696

Figure 2 illustrates a comparison between the original and modified GPx-DTNB procedures