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After the age of 60, the GSH status deteriorates even more drastically

Al mismo tiempo, algunas circunstancias adversas para el organismo, como las inflamaciones, las infecciones o la exposicin a estimulantes nocivos y sustancias contaminantes, pueden aumentar la demanda de glutatin y provocar que se consuma ms rpido de lo que se sintetiza

In the case of metabolic disorders, iron, lipids, and reactive oxygen species (ROS) cannot maintain normal cell function

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Thus, the enhanced GLUT1 expression induced by metformin in our model probably complements its well-established antitumor actions