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But the same location in the peroxidase enzymes is blocked by the protein structure so that substrates can interact only with the heme edge

Pricci, M., Girardi, B., Giorgio, F., Losurdo, G., Ierardi, E., Di Leo, A.: Curcumin and colorectal cancer: from basic to clinical evidences

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This may actually amplify the feelings from beta-alanine -- a 25mg dose is generally the highest we'll go with someone who doesn't want a huge flush, however