semaglutide death rate Patients with type 2 #diabetes and chronic kidney disease are at high risk for kidney failure, cardiovascular events, and death. ⁣ ⁣ Whether treatment with would mitigate these risks is unknown. ⁣ ⁣ Sudden Death in Obesity: Mechanisms

Semaglutide does not require dose adjustment for renal function because it is not cleared renally [1]

the mechanism seems unclear: Drucker explains that GLP-1 doesnt directly get into the brain to a meaningful extent, and how it communicates with the brain is is not well understood in the magic that we see. Given the impact of GLP-1 on appetite control, this seems like a glaring gap in understanding or rather, an important opportunity for future study

These nasal patches may be more tolerable to some people than a CPAP facemask

8 , eabo4271 (2022)

Ten Kulve JS, Veltman DJ, van Bloemendaal L, Groot PFC, Ruh HG, Barkhof F, et al