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On February 21, 2025, FDA declared the national shortage of semaglutide injections resolved and signaled tighter enforcementwhile allowing limited discretion to avoid disrupting active treatment

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The standard 500 mcg oral dose of the arginate form may deliver comparable systemic exposure to much higher doses of the acetate form taken orally

Faverzani JL, Guerreiro G, Hammerschmidt TG, Lopes FF, Coelho D, de Sitta M