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But heres the important part: GLP-1s cause generalized weight loss , not targeted fat reduction

Nonalcoholic steatohepatitis (NASH), the aggressive form of NAFLD, can progress to cirrhosis and hepatocellular cancer (HCC) and is rapidly becoming the leading cause for end-stage liver disease or liver transplantation [3]

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In the first half of the study, Druckers team saw that the GLP-1 drug reduced plaque in the arteries, but the presence or lack of the GLP-1 receptor in blood vessel and immune cells in the aorta did not play a role

It also reduces proatherogenic inflammation, decreasing plasma levels of the inflammatory cytokines TNF- and IFN- and immune cell recruitment [50]