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Therefore, the national and international guidelines recommend GLP1-RA as first-line therapy for adults with T2D with established cardiovascular disease [5, 6]

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While standard, the exclusion of people living with bipolar disorder in many GLP-1 clinical trials means its not fully known how this class of medication affects you if you have the condition

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Tirzepatide, marketed under names like Mounjaro, is another weight loss medication that works similarly to semaglutide, but targets multiple hormones and receptors in the body

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Pharmacogenomics of GPCR drug targets

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Coker, Robert H., et al

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