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The SELECT trial result - 20% reduction in major cardiovascular events with weekly semaglutide 2.4mg in adults with established cardiovascular disease plus overweight/obesity - was the first time a weight-loss medication demonstrated cardiovascular outcome benefits in a major randomized controlled trial

For individuals with an underactive thyroid on stable replacement therapy, there is generally no contraindication to using Wegovy

Keeping up with the Joneses mentality creates comparison pressures that intensify weight struggles beyond simple biological challenges

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Patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use semaglutide