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At week 44, the experimental oral treatment demonstrated a mean weight loss of 8% and 9.8% from baseline for patients receiving 120 mg and 180 mg, respectively

doi:10.1210/jc.2009-1062 30

Another subject, male 70 years of age, developed severe cellulitis of the lower extremity requiring hospitalization 2 wks after the last dose of ARA 290 and suffered a fatal myocardial infarction