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Overall, the model estimated that weight regain would stabilize at about 75 % of the total weight lost during treatment

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26,27 Suggestive evidence of hemoglobin A1c-lowering being the cause of the reported worsening with GLP-1/GIP agonists can be derived by comparing the results of two recent retrospective cohort studies assessing retinopathy outcomes between subjects treated with GLP-1/GIP agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors

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