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So let me write it down as the first time and then I'll put it up again
8, 9, 10 This has been linked to chronic low-level inflammation induced by pro-inflammatory cytokines released by the tumor and tumor-associated macrophages (see review on cachexia in the same issue of this topical issue)
Because the published Phase 2 pharmacology characterizes it as having comparable potency at all three receptors rather than being a single-receptor compound with weak off-target activity
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