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Common side effects for both include mild injection-site reactions, transient water retention, and occasionally a 'flushing' sensation immediately after injection

Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans

10.1016/j.psychres.2011.07.015 Psychiatry Res

In comparison, the more prominent enriched pathways for Low weight loss responders included those related to amino acid and peptide metabolism (glycine, serine, and threonine, d-glutamine and d-glutamate, and tyrosine metabolism and arginine biosynthesis

Normal cells, which do not rely on FOXO4-p53 binding for survival, are unaffected