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(121944) side effects Hypotension, bradycardia (especially if given too rapidly or to patients with cardiac comorbidity)

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Routes that Bypass First-Pass Metabolism: Sublingual (e.g., nitroglycerin) Intravenous (IV) Rectal (partial) Transdermal patches Clinical Significance: Important when dosing oral medications to achieve therapeutic effect

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Blood Sugar Control: Stimulates insulin release and reduces glucagon production, contributing to improved blood sugar control in individuals with type 2 diabetes