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Unknown long-term profile: Human safety data is very limited, so caution and monitoring are advised
Bupropion, an atypical antidepressant, and a dopamine/norepinephrine reuptake inhibitor, is believed to promote weight loss through its stimulatory effect on pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus
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(2018b) reported that TMAO could instigate brain aging and age-related cognitive decline in mice