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Importantly, the gut microbiome functions as an adaptive system that controls metabolism, immune reactions, and neuroendocrine signaling in the host [16-18]

Upon digestion, amino acids and peptides activate calcium-sensing and G-protein-coupled receptors on intestinal L-cells

It occurs naturally in human plasma, though levels decline significantly with age

Rhglp-1 (7-36) protects diabetic rats against cerebral ischemia-reperfusion injury via up -regulating expression of Nrf2/Ho-1 and increasing the activities of sod

Loguercio C, Nardi G, Argenzio F, Aurilio C, Petrone E, Grella A, Del Vecchio Blanco C, Coltorti M