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GLP-1 is a gut hormone that helps regulate appetite, insulin release, and digestion

Phase IIb ran to 24 weeks without reported safety signals

Insulin is the hormone that helps move sugar out of the blood (called glucose) and into your cells for storage and energy

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Preclinical Discovery (2016-2019) Concept and Rationale The scientific foundation for retatrutide emerged from Eli Lillys deep expertise in incretin biology, cultivated over more than two decades of research that also produced tirzepatide (Mounjaro/Zepbound)