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Severe or unusual nausea, vomiting, or diarrhea that differs from your normal semaglutide experience

It is also approved to reduce the risk of major cardiovascular events in adults with obesity or who are overweight with established cardiovascular disease

Regaining weight after you stop taking semaglutide is common

Peer review Peer review information Nature Medicine thanks Christiana Kartsonaki, Naveed Sattar and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Regular exercise, a balanced diet, quality sleep, and stress management can all accelerate how much weight you lose on semaglutide