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First, the study was conducted on a homogeneous population of working dogs with a relatively small number, which may limit the direct generalizability of the results to other canine populations, such as sedentary, geriatric, or juvenile dogs, or those of different breeds

4.1.3 Targeting nerve damage and glial dysfunction A single-center, randomized clinical trial suggests that methylcobalamin was administered may reduce the incidence of BIPN (Zhang et al., 2017)