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Given the identical appearance of the published lesions to VMM, we suspect these patients had physiologic pigmentation, Jonathan D

Ethical approval This study was approved by Institutional Animal Ethics Committee (Proposal no.ECP/IAEC/0042020-21) under the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA, New Delhi, India)

Proinflammatory mediators such as interleukin-6 (IL-6), interleukin-1 (IL-1), and LPS have also been reported to directly stimulate GLP-1 secretion from intestinal endocrine L cells

Nature 412 , 346351 (2001)

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