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Researchers are investigating the combined activity of GLP-1, GIP and glucagon pathways in relation to: Appetite-related signalling Energy balance Energy expenditure Glucose metabolism Substrate and fat metabolism Body-weight regulation Weight-management research models The triple-receptor profile provides researchers with a model for investigating how multiple metabolic signalling pathways may interact within controlled experimental environments

Nevertheless, before these technologies may be clinically translated, there are a number of challenges that need to be conquered

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