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Recruitment of liposomes as topical drug delivery systems would be promising due to their numerous advantages including enhanced skin penetration through the stratum corneum layer, skin moisturizing and restoring effects, controlled drug release, and biocompatibility and biodegradability properties (Rahimpour and Hamishehkar, 2012)

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This study was carried out in accordance with the recommendations of the respective Institutional Review Boards (IRBs), described below with written informed consent from parents of subjects and assent where appropriate