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Counteracting tryptophan metabolism alterations as a new therapeutic strategy for rheumatoid arthritis

Kiss T, Nyl-Tth , Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5

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This paper describes an innovative platform for screening for potential remyelination enhancing agents, and it led to the identification of clemastine, currently in clinical trials

As we age, our natural levels of GHK-Cu decline significantly, which can lead to a plateau in skin resilience and hair density