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doi: 10.1186/s13601-020-00362-7 26 BrandesR

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Interestingly, decreased expression of hephaestin and FPN and increased expression of hepdicin (a protein that promote FPN degradation) suggest these cells accumulate iron and this may contribute to disease worsening

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Fat stores become precious reserves, and muscle protein becomes an acceptable energy and amino acid source

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Most scientific studies available for these unregulated peptides are preclinicalin vitro or animal studieswith little or no clinical trial data

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