Through establishing an interleukin (IL)-1-stimulated chondrocytes, it was found that L-theanine could inhibit the nuclear factor kappa B (NF-B) pathway, thereby reducing the expression of proinflammatory factors, including cyclooxygenase-2 (COX-2), prostaglandin E2, inducible nitric oxide synthase, as well as NO, and protect the degradation of extracellular matrix (30)
Geiger RA, Junghare M, Mergelsberg M, Ebenau-Jehle C, Jesenofsky VJ, Jehmlich N, von Bergen M, Schink B, Boll M (2019) Enzymes involved in phthalate degradation in sulphate-reducing bacteria
What does the Phase II trial data show
Do not push too hard as this will lock the lid
Based on immunological studies, - glucans considered active compounds to induce immune effects and initiate anti-microbial immune responses and anti-tumor activities