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However, no difference in the OCR profiles of mutant and control FoB was detected upon treatment with oligomycin A (Fig

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Furthermore, given that we have demonstrated that this mitochondrial adaptation is to promote rebalancing of pyrimidine levels, mitochondrial biogenesis could also be used to identify patient cohorts likely to benefit from UCK2 inhibitor combinations

Community-reported KLOW doses cluster around 250-500 mcg per component per injection, daily for 4-6 weeks