Methionine also supports cellular redox potential maintenance by generating antioxidants like taurine and glutathione (Alharthi et al., 2018), participates in phosphatidylcholine synthesis (Vance and Tasseva, 2013), and facilitates de novo synthesis of nucleotides (Girard and Matte, 2005)
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Similarly, many Gram-positive bacteria chromosomally encode efflux pumps that expel certain antibiotics, such as fluoroquinolones and macrolides
Fatigue is uncommon in clinical trials (under 1%) but may be more frequently reported in real-world use, especially during the early weeks of treatment