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Low titers of serum autoantibodies, such as antinuclear antibodies (ANA) and anti-smooth muscle antibodies (SMA), are commonly observed in MASLD (34 %) often as incidental findings without clinical significance [6]

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For example, thyroxine is needed to enhance GH effects on endocrine IGF-I expression and a normal GH-IGF-IGFBP-axis is needed for optimal thyroid hormone production (77)

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