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A complementary axis involves transcriptional reinforcement of antioxidant programs, including NFE2 like BZIP transcription factor 2 (NFE2L2, also known as NRF2) signaling, which increases GPXs and further suppresses ROS-driven inflammasome activation 58

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Abstract The vermiform appendix is a muscular cylindrical structure originating near the junction of the cecum and ileum, averaging 9 cm (535 cm) in size