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Regarding mitochondrial dysfunction involved in AD pathophysiology, it includes disturbances in oxidative phosphorylation (OXPHOS), and impaired energy metabolism as well as excess generation of ROS, altered mitochondrial biogenesis, transport and dynamics (68)

The high cost of GLP-1 RAs may create a system where effective obesity treatment is available only to those with adequate insurance coverage or financial resources

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In: Wang Y-X, editor

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