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According to a meta-analysis evaluating five adult NAFLD cohort studies, the presence of advanced fibrosis (stage 2 or more) is the most important predictor of liver-related mortality in NAFLD patients [9]

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Historically, erythema multiforme major (EMM) has been particularly difficult to differentiate from SJS/TEN [67]

These additives prevent ice crystal formation or protect the peptide structure during the freeze-thaw process