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Lee et al., 2012

In diet induced obese mouse models and genetic obesity and diabetes models, the five agonists showed better weight loss effect, reduced food intake and improved hyperglycemia than GLP-1: GIP or smeglutide

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AMG 133 Phase I results Are GLP-1 Weight Loss Drugs the Next Blockbusters

Many patients report naturally skipping meals or finishing plates halfway through without feeling deprived