Avoid repeated freezethaw cycles, keep vials out of direct light, and label each one with its reconstitution date so results stay reproducible from run to run
McIntyre et al ., Reference McIntyre, Berk, Brietzke, Goldstein, Lpez-Jaramillo, Kessing, Malhi, Nierenberg, Rosenblat, Majeed, Vieta, Vinberg, Young and Mansur2020, Reference McIntyre, Alsuwaidan, Baune, Berk, Demyttenaere, Goldberg, Gorwood, Ho, Kasper, Kennedy, Ly-Uson, Mansur, McAllister-Williams, Murrough, Nemeroff, Nierenberg, Rosenblat, Sanacora, Schatzberg, Shelton, Stahl, Trivedi, Vieta, Vinberg, Williams, Young and Maj2023)
Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A et al
doi: 10.1007/s11897-013-0133-0 20
Because it is absorbed more efficiently at the cellular level, there is less unabsorbed material to cause irritation or digestive distress