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All methods of the current study were carried out in accordance with relevant ethical guidelines and regulations of the ARRIVE guidelines
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T.TramontinA
BBA-Gen Subj 2017;1861:181324
Notably, SPP1 + TAM showed an increased expression of VEGF and Syndecan-2 (SDC2) (69), a transmembrane proteoglycan that binds MMP-2, a metalloprotease released by endothelial cells upon hypoxic conditions ( SPP1 + TAM and tumor endothelial cells promotes tumor angiogenesis
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