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Understanding GLP-1 dosing: Starting low and titrating up All GLP-1 medications (glucagon-like peptide-1 receptor agonists) are initiated at a low dose and their dosage is gradually escalated over time to enhance your bodys tolerability and minimize the risk of side effects, particularly gastrointestinal side effects such as nausea, vomiting, diarrhea, and constipation

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Hence, the diameter of the pigmented lesions is usually less than 1 cm, and their morphology is flat, solitary, and well-circumscribed ( Figure 1A )

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