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(2014) 4(12):e005360

These results may be compared with those of a post hoc analysis of the LEADER trial, which demonstrated similar incidence rates of MACE in the liraglutide vs placebo group in subjects with a relatively low baseline CV risk (defined as isolated CKD, hypertension with left ventricular hypertrophy, New York Heart Association Class II or III heart failure, and left ventricular systolic or diastolic dysfunction) [37]

MOTS-c is a mitochondrial-derived peptide being studied for metabolic signaling and stress-response biology

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