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In a phase 2B study of lanifibranor, the percentage of patients who achieved at least a two-point reduction in the SAF-A score without fibrosis progression was significantly higher among those receiving the 1,200-mg dose compared to placebo (1,200-mg dose vs

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CrossRef Use and effectiveness of dapagliflozin in patients with type 2 diabetes mellitus: a multicenter retrospective study in Taiwan Jung-Fu Chen, Yun-Shing Peng, Chung-Sen Chen, Chin-Hsiao Tseng, Pei-Chi Chen, Ting-I Lee, Yung-Chuan Lu, Yi-Sun Yang, Ching-Ling Lin, Yi-Jen Hung, Szu-Ta Chen, Chieh-Hsiang Lu, Chwen-Yi Yang, Ching-Chu Chen, Chun-Chuan Lee, Pi-Jung Hsiao, Ju-Ying Jiang, S PeerJ.2020

While progress in this area has slowed because of the challenges involved in HIV infection in rodents and limited access to nonhuman primates, the development of new rodent model systems and sophisticated cocultures and organoids has the potential to rapidly advance these important studies