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All discrepancies between reviewers were resolved through consensus-based discussions with a senior researcher (LZ)

This is a critical feature because it dramatically reduces "dead space"the small amount of fluid left in the needle hub after the plunger is fully depressed

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10.1016/S0140-6736(18)31129-2 95 LubbersK.HiralalK

The endoscopic and histologic features vary, ranging from mild inflammatory changes with submucosal hemorrhages (peridiverticular red spots on colonoscopy sometimes referred to as "Fawaz spots") to florid, chronic active inflammation resembling (histologically and endoscopically) inflammatory bowel disease The pathogenesis is incompletely understood