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Consequently, there was a significant decrease in mitochondrial glutathione (mGSH) levels in the kidneys [22]

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Strengths of the present meta-analysis are the inclusion of all CVOTs published by 10 December 2021, the very large number of participants, the high quality of the trials which minimizes the risk of bias, and the absence of significant heterogeneity in most analyses, which ranged from absent to low or moderate

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