10 November 2025 A Correction to this paper has been published: Abbreviations AGEs: Advanced glycation end products AKT2: AKT serine/threonine kinase-2 Apaf-1: Apoptotic protease-activating factor-1 AR: Androgen receptors ARKO: Androgen receptor knockout ATP: Adenosine triphosphate BCAAs: Branched-chain amino acids BPA: Bisphenol A BTB: The blood-testis barrier CAT: Catalase CBT: Cognitive behavioral therapy CHOP: C/EBP homologous protein CML: Carboxymethyl lysine CRP: Reactive protein DM: Diabetes mellitus ED: Erectile dysfunction EGCG: Epigallocatechin gallate eNOS: Endothelial nitric oxide synthase ER: Endoplasmic reticulum FSH: Follicle-stimulating hormone GLUT4: Glucose transporter 4 GnRH: Gonadotropin-releasing hormone GSH-Px: Glutathione peroxidase HATs: Histone acetyltransferases HbA1c: Glycated hemoglobin A1c HH: Hypogonadotropic hypogonadism HPG: Hypothalamic-pituitary-gonadal HPT: Hypothalamic-pituitary-testicular hs-CRP: High-sensitivity C-reactive protein IL-1: Interleukin-1 IR: Insulin resistance IR-: Insulin receptor subunit IRS-1: Insulin receptor substrate 1 JNK: c-Jun N-terminal kinase LH: Luteinizing hormone lncRNAs: long non-coding RNAs LR: Inflammation-related ligand-receptor MDA: Malondialdehyde MetS: Metabolic syndrome MFI: Male factor infertility miRNAs: MicroRNAs MMAF: Multiple morphological abnormalities of the sperm flagella MMP: Mitochondrial membrane potential mPTP: Mitochondrial permeability transition pores mTOR: Mechanistic target of rapamycin NO: Nitric oxide OP-2: Water-soluble okra polysaccharide PiRNAs: PIWI-interacting RNAs PI3K: Phosphoinositide 3-kinase PPARs: Peroxisome proliferators-activated receptors RAGE: Advanced glycation end products ROS: Reactive oxygen species SHBG: Sex hormone-binding globulin siRNAs: Small interfering RNAs SLC2A4: Solute carrier family 2 member 4 snoRNAs: Small nucleolar RNAs SOD: Superoxide dismutase SREBPs: Sterol-regulatory element binding proteins STZ: Streptozotocin T1DM: Type 1 diabetes mellitus T2DM: Type 2 diabetes mellitus TCA: Tricarboxylic acid TNF-: Tumor necrosis factor- TRT: Testosterone replacement therapy TZDs: Thiazolidinediones UPR: Unfolded protein response 1-NP: 1-Nitropropene 8-oxoG: The mutagenic 8-oxoguanine References Li Y, et al
These medications belong to a class of glucagon-like peptide-1 (GLP-1) receptor agonists and are marketed under brand names such as Ozempic, Wegovy, Victoza, and Saxenda
These multivitamin gummies contain Vitamin D3 and Calcium for bone support(1), Vitamins D, C & zinc for immune support(1), 6 B vitamins to support energy metabolism(1), and Vitamin A to support hair skin & nails(1)
It is visceral fat, the deep abdominal fat that surrounds the organs
Results without dietary awareness are possible but less impressive
