weight regain and cardiometabolic effects after withdrawal of semaglutide Two-year in adults with overweight or obesity: the STEP 5 trial Weight maintenance after discontinuation of

However, some people continue experiencing mild intermittent nausea, particularly if they eat too much at once or consume especially rich foods

This randomized, double-blind, placebo-controlled trial showed that treatment with semaglutide alleviated pain related to osteoarthritis of the knee among persons with obesity and knee osteoarthritis, Bliddal and colleagues wrote

2025;8(1):e2457349

[DOI] [PubMed] [Google Scholar] 86.Carranza-Naval M.J., Del Marco A., Hierro-Bujalance C., Alves-Martinez P., Infante-Garcia C., Vargas-Soria M., Herrera M., Barba-Cordoba B., Atienza-Navarro I., Lubian-Lopez S., et al

Taking Semaglutides for off-label uses is not recommended and may have health and safety implications