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5.2 Parkinsons disease Parkinsons disease is the second most common chronic and late-onset neurodegenerative disease after Alzheimers disease, with clinical features including slowness of facial expression, increased muscle tension throughout the body, bradykinesia, progressive resting tremor, and dementia (Nishioka and Hattori, 2020)

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The soft tissue injury model was established by mechanical stress

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Among 207 genephenotype analyses, only 14 reached nominal significance, and none remained significant after Bonferroni correction