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Indeed, over 110 different compounds, including metals, their oxides, metal salts, drugs, kinase inhibitors, endogenous toxins, inhibitors of signaling pathways, alkaloids and other plant-derived biologically active substances, have been shown to induce eryptosis in vitro at lower concentrations than hemolysis or to a higher extent at the same concentrations [450]

These interventions also partially restored gut barrier integrity, reduced renal IgG deposition, and significantly improved kidney function [86]

(2022) found that Aspergillus (GAS) activated the Nrf2/HO-1 pathway by upregulating HO-1 expression, which enhanced antioxidant capacity, reduced free iron accumulation, and ultimately inhibited ferroptosis in a rat model of VaD

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